The Esco Medical MIRI® II-12 incubator is intended to be used to provide a stable culture environment at or near body temperature and CO₂/N₂ gases for the development of gametes and embryos during in vitro fertilization (IVF) / assisted reproduction technology (ART) treatments.

To ensure maximum performance, the system of MIRI® II-12 has 24 completely separate PID temperature controllers. They control and regulate the temperature in culture chambers and lids. Compartments do not affect each other's temperatures in any way. The top and the bottom of each compartment are separated with a PET layer so that the lid temperature would not affect the bottom. For validation purposes, each compartment has a PT-1000 sensor built-in. The circuitry is separated from the unit's electronics, so it remains a genuinely separate validation system.

The incubator needs 100% CO2 and 100% N2 to control CO2 and O2 concentrations in the culture chambers. A dual-beam infra-red CO2 sensor with extremely low drift rates controls the CO2 level. A chemical, medical-grade oxygen sensor controls the level of O2.

Gas recovery time is less than 3 minutes after opening the lid. MIRI® II-12 incubator is fitted with 12 gas sample ports that allow the user to validate gas concentration by sampling gas from the individual compartment.

The incubator also features a recirculated gas system where gas is continuously put into the compartment and taken out at the same rate. Gas is cleaned via 254 nm UVC light with direct gas contact between the bulb and gas, then through a VOC filter and a HEPA filter. The UVC light has filters that inhibit any 185 nm radiation that would produce dangerous ozone. The VOC filter is located under the UVC light. The complete gas repletion in the system takes less than 5 minutes.